With more than 20 therapeutic antibody-based drugs already on the market, in which more than 100 in clinical trials. it is obviously that the antibody therapeutic area has played an important role in the pharmaceutical industry. The specificity of antibody binding is a key focus and challenge in the discovery and development of therapeutic antibody. Scientists have applied multiple strategies such as protein arrays, Western blots, immunohistochemical stains and small peptide libraries to evaluate antibody specificity. However, these methods have some significant limitations.
BOC Sciences has introduced our proprietary peptide HTS library synthesis platform, incorporating an advanced fully automated workstation synthesizer to enable high-throughput synthesis of peptide libraries with industry-leading speed and flexibility. With the library synthesis platform, our team is able to precisely control peptide library synthesis, significantly improving throughput and accuracy.
Application
- Interaction analysis
- Antibody repertoire profiling
- Quantitative antibody binding specificity measurements
Figure 1. HTS and sequence analysis strategy. (Inmaculada, R. R.;.; et al. 2014)
Our Capabilities
- High throughput
- Top quality
- Fast turnaround time
- Flexible services
The peptide HTS library synthesis platform can deliver a high throughput production
BOC Sciences employs fully automatic production to precisely control synthesis conditions and material additions which can significantly reduce the instability and other error
Our peptide HTS library platform is able to conduct sequence analysis to determine the most efficient production approach and increase production efficiency
We provide conventional peptide library and micro-peptide library services according to different customer needs, and additional QC testing services are also provided.
Features of Our Peptide HTS library
- No cross-contamination
- High-throughput 96-well format
- Comprehensive modifications, including biotin, FITC, phosphorylation, etc
BOC Sciences provides professional, rapid and high-quality services of Peptide HTS library design at competitive prices for global customers. Personalized and customized services of Peptide HTS library design can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!
Reference
- Inmaculada, R. R.; et al. Identification of target-binding peptide motifs by high-throughput sequencing of phage-selected peptides. Nucleic Acids Research. Nucleic Acids Research. 2014. 42(22).
