In order to perform efficient antigen-specific stimulation in T-cell assays such as ELISPOT and flow cytometry, BOC Sciences has constructed top-quality peptide pools. Our team adheres to BOC Sciences' gold standard for peptide pools building, upholding the highest quality and batch-to-batch consistency to maintain strict quality control throughout the manufacturing process in accordance with industry regulations. We also make sure that no false positive T-cell responses are obtained in the generated peptide pools by contaminating peptides or toxic inhibition caused by-products.
Figure 1. hUGT1A1 Epitope Location within Peptide Pool A. (Greig, J. A.; et al. 2018)
Our Services
BOC Sciences is committed to providing you with tailor-made peptide pools suitable for research use or clinical applications. We have the ability to offer different antigens and new epitopes, new pool layouts.
- Infectious disease antigens
- Control pools
- Tumor-associated antigens
- Electromagnetic pulse
We offer many different pathogens available as ready-to-use peptide pools such as SARS-CoV-2, EBV, HCMV, Influenza, HAdV
Appropriate positive and negative controls (e.g. CEF or CEFX pools) are supported to establish reliable and validated T-cell assays
Our carefully designed peptide pools are able to cover tumor-associated antigens from human and other organisms (e.g. MAGE, NY-ESO1, PSA, WT1)
BOC Sciences offers epitope mapping peptide sets consisting of matrix pools in combination with individual peptides for rapid identification of epitopes within antigens
What we Deliver?
- At BOC Sciences, peptide arrays are provided in a variety of sizes and formats according to the demand of different projects
- LC-MS on marker peptides (up to 8) in final pool to guarantee presence of all peptides within the final pool
- Standard delivery times of around 3-4 weeks depending on different pool size
- Delivered as 96-well plate or 100-tube rack
- CCOA, MS, and HPLC validation data for each peptide before pooling are provided
BOC Sciences provides professional, rapid and high-quality services of Peptide Pools design at competitive prices for global customers. Personalized and customized services of Peptide Pools design can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!
Reference
- Greig, J. A.; et al. AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver. Molecular Therapy-Methods & Clinical Development. 2018,.11: 191-201.
