We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy
Cyclization modifications can confer several advantages to peptides that cumulatively make them more drug-like. Constraining peptides via cyclization is a common strategy to mimic (protein) secondary structures (e.g. peptide rings) or to create peptides with enhanced conformational stability (compared to their linear analogs).
Aiming to construct a top-quality -peptide cyclization library, BOC Sciences has established several reaction platforms to create various types of conformationally-constrained peptides with robust reactions and high yields.
Figure 1. One step cleavage and cyclization of unprotected peptides with the KAHA ligation. (Florian, R.; et al. 2015)
BOC Sciences provides professional, rapid and high-quality services of Peptide Cyclization Library design at competitive prices for global customers. Personalized and customized services of Peptide Cyclization Library design can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!
Reference
BOC Sciences has rich experience in working with global customers in custom library synthesis of compounds and generating small to medium-sized libraries of target compounds. Our knowledge in generating a large number of target molecules in a remarkably shorter time enables quick biological screenings for affinities. With the target properties in mind, we deliver target molecules, by applying our extensive knowledge in drug discovery.