Viruses are tiny (microscopic) infectious agents that grow and multiply only inside the living cells of an organism. Viruses have receptors that allow them to attach to healthy (host) cells in the body. Once a virus attaches to and enters a host cell, it can replicate quickly. The host cell dies and the virus then infects other healthy cells. Antiviral drugs help the immune system fight off the harmful virus. These drugs can ease symptoms and shorten the length of a viral infection.
BOC Sciences can design a 2D similarity-based antiviral library based on known structure and activity data for some available virus-targeting compounds.
Figure 1. Schematic representation of influenza virus attachment, internalization, replication and exit from the host respiratory cell and steps inhibited by antiviral drugs. (Stiver, G. 2003)
This library is established using 2D fingerprint similarity searches against a reference set of over 40,000 bioactive compounds that are carefully selected from multiple commercial databases. BOC Sciences applies the following therapeutically relevant viral assays representing different viral species and their proteins of interest to generate it:
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BOC Sciences provides professional, rapid and high-quality services of 2D Similarity-based Antiviral Library design at competitive prices for global customers. Personalized and customized services of 2D Similarity-based Antiviral Library design can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!
Reference
BOC Sciences has rich experience in working with global customers in custom library synthesis of compounds and generating small to medium-sized libraries of target compounds. Our knowledge in generating a large number of target molecules in a remarkably shorter time enables quick biological screenings for affinities. With the target properties in mind, we deliver target molecules, by applying our extensive knowledge in drug discovery.