The initial stage of new peptide drug development is mainly the discovery and structure optimization process of drug lead compounds. In this process, medicinal chemists do not require a large amount of target peptides, but have a high demand for their sequence structural diversity. Therefore, it is of great importance to rapidly construct micro-scale peptide library containing a large number of structurally diverse members for the corresponding medicinal chemistry studies. Unlike conventional peptide libraries that provide milligram-level peptides, micro-peptide libraries contain peptides at micromolar scales, and are more suitable for preliminary screening for targeted proteomics, target screening and antigenic epitopes applications.
Figure 1. Peptide microarrays do not fully capture interactions detected by peptide pulldowns. (Petell, C. J.; et al. 2019)
Application
- Targeted Proteomics
- Protein response monitoring
- Protein abundance in metabolic pathways analysis
- Protein subunits stoichiometry assessment
- Phosphorylation levels in signaling pathways identification
- Biomarker expression in serum evaluation
- Monitor protease activity
- Protease substrates identification using fluorescence spectroscopy
- Peptide screening
What we Deliver?
- At BOC Sciences, peptide arrays are provided in a variety of sizes and formats according to the demand of different projects
- Peptide lengths can be ranging from 5 to 30 amino acids, which can meet most requirement of applications
- Our expert teams can provide peptide library containing up to 50 amino acid if there is special demand
- Standard delivery times of around 3-4 weeks depending on different library size and peptide length
- Delivered as freeze-dried in 96-well plates for subsequent experiments
- Analytical MS and HPLC data are available for each peptide product
- BOC Sciences offers standard TFA removal service according to the customer's requirements
BOC Sciences provides professional, rapid and high-quality services of Micro-scale Peptide library design at competitive prices for global customers. Personalized and customized services of Micro-scale Peptide library design can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!
Reference
- Petell, C. J.; et al. Improved methods for the detection of histone interactions with peptide microarrays. Scientific Reports. 2019. 9(1).
